Purpose

Breakthroughs that change patients' lives... At Pfizer we are a patient centric company, guided by our four values: courage, joy, equity and excellence. Our breakthrough culture lends itself to our dedication to transforming millions of lives.


Position Summary

To support manufacture and development of novel products for worldwide clinical trials in a safe and efficient manner in the API Process Development Facility B902 Pilot Plant, following all approved procedures and best practices in safety, compliance, and manufacturing operations.

POSITION RESPONSIBILITIES

• Undertake training to execute API manufacturing processes under the appropriate level of supervision for grade:
• preparing equipment for use.
• preparing, collecting, dispensing processing materials, and handling materials through the process lifecycle.
• running the process, observing the process and recording observations and technical excursions on batch records.
• Cleaning and testing the process equipment after use.

Undertake training and demonstrate:

• good cGMP documentation practices to all documents related to API manufacture.
• an understanding and ability to follow Standard Operating instructions.
• a good working knowledge of these procedures/instructions to ensure safe and compliant operation of equipment and execution of processing operations.
• a sound operational knowledge of the facilities process control system.
• competency to participate in safety inspections within the facility when required.
  • Work towards a full understanding of cGMP concepts in the manufacture of API's for use in clinical trials.
  • Understand and comply with the policies, procedures and working practices of EH&S (e.g. Risk assessments, COSHH) and where necessary contribute to the review and implementation of the practices in the plant.
  • Understand Inventory Management processes and follow Emergency and lone working procedures.
  • Through team work assist in the delivery of Projects to agreed timelines.
  • Demonstrates a flexible attitude to working patterns, executing the role with enthusiasm and diligence.
  • Supports the facilities operations during normal plant operating hours.
  • Provide Process Supervisors with observations associated with API manufacture.
  • Work and share knowledge with the support services for the relevant API Manufacturing facility to ensure the continual smooth operation of processing within the plant. E.g. FM&E engineering.
  • Take ownership and responsibility for good housekeeping standards in the facilities.

Definitions for acronyms:

API Active Pharmaceutical Ingredient.

COSHH Control of Substances Hazardous to Health.

cGMP current Good Manufacturing Practices.

EH&S Environment, Health and Safety.

FM&E Facility Management and engineering.

EDUCATION AND EXPERIENCE

Tech Ops 1 requirement:

GCSE qualification with at least grade C (or 4) in Chemistry and Physics required, "A" level qualification in Chemistry/Physics highly desired. BTEC and international Baccalaureate (and equivalent certificates) will be considered.

Tech Ops 2 requirement:

Qualifications as above, plus familiarity with current Good Manufacturing Practices (cGMPs) and EH&S along with experience in a manufacturing and/or research and development environment is required.

TECHNICAL SKILLS REQUIREMENTS

Familiarity and willingness to learn software programs; Word, Excel, Outlook, etc

PHYSICAL POSITION REQUIREMENTS

Candidate must be physically capable of working in a pharmaceutical manufacturing facility, be amenable to wearing personal protective equipment, and working with hazardous materials. Lifting of material containers, movement of pallets of drums using pallet jacks and other manual tasks may be required periodically. This position involves integration of novel equipment platforms and processing chemistry steps into a manufacturing environment that operates at least 16 hours each weekday. Candidate must be able and willing to accommodate a work schedule that includes a weekly rotating shift cycle and at times could flex throughout that operating range and perhaps extend beyond 8 hours per day.



Closing deadline for applications is September 22nd.

All applicants must have the relevant authorisation to live and work in the UK.